MX2 is an interferon-induced inhibitor of HIV-1 infection

作者: Melissa Kane , Shalini S. Yadav , Julia Bitzegeio , Sebla B. Kutluay , Trinity Zang

DOI: 10.1038/NATURE12653

关键词:

摘要: HIV-1 replication can be inhibited by type I interferon (IFN), and the expression of a number of gene products with anti-HIV-1 activity is induced by type I IFN 1 , 2 . However, none of the …

参考文章(30)
JWB Bainbridge, C Stephens, K Parsley, C Demaison, A Halfyard, AJ Thrasher, RR Ali, In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium. Gene Therapy. ,vol. 8, pp. 1665- 1668 ,(2001) , 10.1038/SJ.GT.3301574
C. Ochsenbauer, T. G. Edmonds, H. Ding, B. F. Keele, J. Decker, M. G. Salazar, J. F. Salazar-Gonzalez, R. Shattock, B. F. Haynes, G. M. Shaw, B. H. Hahn, J. C. Kappes, Generation of Transmitted/Founder HIV-1 Infectious Molecular Clones and Characterization of their Replication Capacity in CD4 T-Lymphocytes and Monocyte-derived Macrophages Journal of Virology. ,vol. 86, pp. 2715- 2728 ,(2012) , 10.1128/JVI.06157-11
KyeongEun Lee, Zandrea Ambrose, Thomas D. Martin, Ilker Oztop, Alok Mulky, John G. Julias, Nick Vandegraaff, Joerg G. Baumann, Rui Wang, Wendy Yuen, Taichiro Takemura, Kenneth Shelton, Ichiro Taniuchi, Yuan Li, Joseph Sodroski, Dan R. Littman, John M. Coffin, Stephen H. Hughes, Derya Unutmaz, Alan Engelman, Vineet N. KewalRamani, Flexible Use of Nuclear Import Pathways by HIV-1 Cell Host & Microbe. ,vol. 7, pp. 221- 233 ,(2010) , 10.1016/J.CHOM.2010.02.007
Elena Sokolskaja, David M. Sayah, Jeremy Luban, Target Cell Cyclophilin A Modulates Human Immunodeficiency Virus Type 1 Infectivity Journal of Virology. ,vol. 78, pp. 12800- 12808 ,(2004) , 10.1128/JVI.78.23.12800-12808.2004
K A Mitrophanous, S Yoon, J B Rohll, D Patil, F J Wilkes, V N Kim, S M Kingsman, A J Kingsman, N D Mazarakis, Stable gene transfer to the nervous system using a non-primate lentiviral vector Gene Therapy. ,vol. 6, pp. 1808- 1818 ,(1999) , 10.1038/SJ.GT.3301023
Ann M. Sheehy, Nathan C. Gaddis, Jonathan D. Choi, Michael H. Malim, Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein Nature. ,vol. 418, pp. 646- 650 ,(2002) , 10.1038/NATURE00939
J. Bitzegeio, M. Sampias, P. D. Bieniasz, T. Hatziioannou, Adaptation to the Interferon-Induced Antiviral State by Human and Simian Immunodeficiency Viruses Journal of Virology. ,vol. 87, pp. 3549- 3560 ,(2013) , 10.1128/JVI.03219-12
Stuart J. D. Neil, Trinity Zang, Paul D. Bieniasz, Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu Nature. ,vol. 451, pp. 425- 430 ,(2008) , 10.1038/NATURE06553