Survival rates of patients with metastatic malignant melanoma.

摘要: Malignant melanoma (MM) is the cutaneous neoplasia with greatest mortality rates and one of malignancies highest potential dissemination. The prognosis patients metastatic MM grim, a 5-years survival rate between 5- 19%, dictated by location number metastases. Objective: We aimed to estimate from our study find out if metastasis' influences survival. Methods results: Between 2008 2013, 155 were diagnosed in clinic. All staged according 2009 AJCC staging system. median follow-up period was 24 months. Survival calculated using Kaplan-Meier method confidence level 95%. 40.5% developed metastases different organs, especially brain. 80.6% those died during study. overall survival, estimated for entire group who metastases, 5.3 Discussion: influence distribution on examined it noticed that there statistically significant differences risks death various groups patients, depending metastasis topography. Thus, probability patient brain twice digestive metastasis, about 7 times higher than lung (p = 0.0004) 12 risk extra-regional lymph nodes or subcutaneous 0.0000).