ROLE OF CONTINUOUS COMPONENT IN SUBCUTANEOUS "OPEN-LOOP" INSULIN DELIVERY
作者： JillD. Nelson , A.Michael Albisser , ErrolB. Marliss , Bernard Zinman
DOI: 10.1016/S0140-6736(80)92654-9
关键词:
摘要: Abstract To determine the role of continuous component in open-loop subcutaneous insulin-infusion systems plasma-glucose and "free" immunoreactive insulin (IRI) levels were compared nine lean insulin-dependent diabetics receiving via a catheter either as premeal boluses plus infusion (SCI) or alone before meals at bedtime (SCB). Subjects first placed on intravenous closed-loop system to requirements (42±2·5 U/day) for ideal control. With diet total kept constant, identical nearly normal profiles obtained with both SCB SCI during meals. The mean excursions 68±10 mg/dl breakfast, 28±14 lunch, 32±10 dinner. Plasma-glucose remained after dinner until 3 A.M. (93±8 mg/dl), but by 7A.M. level achieved was 284±18, while that 96±11 (p
sci-hub.se 参考文章(19)
A. K. Hanna, H. L. Mlnuk, A. M. Albisser, E. B. Marliss, B. S. Leibel, B. Zinman, A Portable System for Continuous Intravenous Insulin Delivery: Characteristics and Results in Diabetic Patients Diabetes Care. ,vol. 3, pp. 1- 8 ,(1980) , 10.2337/DIACARE.3.1.1
A. E. Lambert, M. Buysschaert, L. Lambotte, Use of an artificial pancreas as a tool to determine subcutaneous insulin doses in juvenile diabetes Diabetes Care. ,vol. 2, pp. 256- 264 ,(1979) , 10.2337/DIACARE.2.3.256
J.C. Pickup, H. Keen, M.C. White, J.A. Parsons, K.G.M.M. Alberti, LONG-TERM CONTINUOUS SUBCUTANEOUS INSULIN INFUSION IN DIABETICS AT HOME The Lancet. ,vol. 314, pp. 870- 873 ,(1979) , 10.1016/S0140-6736(79)92686-2
David S. Schade, R.P. Eaton, William Spencer, Richard Goldman, Wayne T. Corbett, The peritoneal absorption of insulin in diabetic man: a potential site for a mechanical insulin delivery system. Metabolism-clinical and Experimental. ,vol. 28, pp. 195- 197 ,(1979) , 10.1016/0026-0495(79)90064-7
WilliamV. Tamborlane, RobertS. Sherwin, Myron Genel, Philip Felig, RESTORATION OF NORMAL LIPID AND AMINOACID METABOLISM IN DIABETIC PATIENTS TREATED WITH A PORTABLE INSULIN-INFUSION PUMP The Lancet. ,vol. 313, pp. 1258- 1261 ,(1979) , 10.1016/S0140-6736(79)92226-8
G. Tchobroutsky, Relation of diabetic control to development of microvascular complications. Diabetologia. ,vol. 15, pp. 143- 152 ,(1978) , 10.1007/BF00421230
SAUL M. GENUTH, Plasma insulin and glucose profiles in normal, obese, and diabetic persons. Annals of Internal Medicine. ,vol. 79, pp. 812- 822 ,(1973) , 10.7326/0003-4819-79-6-812
P. Raskin, P. Angel, R. Unger, Changes in Glucagon Levels After Four to Five Weeks of Glucoregulation by Portable Insulin Infusion Pumps Diabetes. ,vol. 28, pp. 1033- 1035 ,(1979) , 10.2337/DIAB.28.11.1033
Amir K. Hanna, Bernard Zinman, Azima F. Nakhooda, Howard L. Minuk, Elaine F. Stokes, A.Michael Albisser, Bernard S. Leibel, Errol B. Marliss, Insulin, glucagon, and amino acids during glycemic control by the artificial pancreas in diabetic man. Metabolism-clinical and Experimental. ,vol. 29, pp. 321- 332 ,(1980) , 10.1016/0026-0495(80)90005-0
A. E. Kitabchi, J. N. Fisher, G. A. Burghen, M. S. Gaylord, N. M. Blank, Evaluation of a portable insulin infusion pump for outpatient management of brittle diabetes. Diabetes Care. ,vol. 2, pp. 421- 424 ,(1979) , 10.2337/DIACARE.2.5.421