作者: S. C. Cannegieter , F. R. Rosendaal , M. Kloppenburg , T. W. J. Huizinga , A. L. Huidekoper
DOI: 10.1093/RHEUMATOLOGY/KET212
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摘要: OBJECTIVES: There are conflicting reports concerning the association between alcohol consumption and RA. We performed a case-control study to investigate of with RA as well other forms arthritis. To assess whether affects long-term disease outcome, we also investigated its radiographic progression sustained drug-free remission in METHODS: Patients arthritis various diagnoses including RA, OA, ReA, SpA PsA were compared 5868 controls from general population. The was analysed by logistic regression analysis. RESULTS: Alcohol inversely associated not only [odds ratio (OR) 0.28, 95% CI 0.23, 0.35] but OA (OR 0.31, 0.16, 0.62) 0.34, 0.24, 0.48). A higher degree systemic inflammation, reflected ESR CRP level, smaller proportion patients consuming alcohol. no dose-response relationship amount consumed presence extent joint destruction rate affected consumption. CONCLUSION: Arthritis report less than controls, regardless type This suggests that may either protect against different kinds or inverse be secondary development, being inclined consume due their decreased well-being.