Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance

作者: David Mavor , Kyle A. Barlow , Daniel Asarnow , Yuliya Birman , Derek Britain

DOI: 10.1242/BIO.036103

关键词:

摘要: Although the primary protein sequence of ubiquitin (Ub) is extremely stable over evolutionary time, it is highly tolerant to mutation during selection experiments performed in the …

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