Effects of repetitive transcranial magnetic stimulation on children with low‐function autism

摘要: Background Autism spectrum disorder (ASD) is a very complex neurodevelopmental disorder, characterized by social difficulties and stereotypical or repetitive behavior. Some previous studies using low-frequency transcranial magnetic stimulation (rTMS) have proven of benefit in ASD children. Methods In this study, 32 children (26 males six females) with low-function autism were enrolled, 16 (three females 13 males; mean ± SD age: 7.8 2.1 years) received rTMS treatment twice every week, while the remaining 7.2 1.6 served as waitlist group. This study investigated effects on brain activity behavioral response autistic Results Peak alpha frequency (PAF) an electroencephalographic measure cognitive preparedness might be neural marker function for autism. Coherence one way to assess functional connectivity children, which has abnormal studies. The results showed significant increases PAF at frontal region, left temporal right region occipital increase coherence between central region. Behavior Checklist (ABC) scores also compared before after receiving positive shown Conclusion These findings supported our hypothesis demonstration combined neurotherapy active group group, improvements outcomes