In vitro and in vivo antioxidant activity of the pulp of Jatobá-do-cerrado

作者: Daniela Granja ARAKAKI , Camila Jordão CANDIDO , Anderson Fernandes da SILVA , Rita de Cássia Avellaneda GUIMARÃES , Priscila Aiko HIANE

DOI: 10.1590/1678-457X.0084

关键词:

摘要: Oxygen metabolism in cells causes the production of free radicals, which produce damage, including changes cell structure and function. Antioxidants are substances that, at low concentrations, slow down or prevent oxidation. Fruits vegetables contribute to dietary supply these compounds. The flora Cerrado Brazil has shown have high levels bioactive This study aimed characterize antioxidant activity pulp jatoba-do-cerrado vitro vivo.In aqueous, ethanol aqueous acetone extracts was evaluated by DPPH method. We determined total phenols Folin-Ciocalteu assay tannins Folin-Denis method.In vivo potential extract TBARS technique. had highest capacity, followed extracts. same pattern occurred extraction tannins. In administration inhibited lipid peroxidation compared control group. inhibition increased elevating dosage concentration extracts, demonstrating a significant as well vitro.

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