Furostanol saponins and quercetin glycosides from the leaves of Helleborus viridis L.

作者: Alessandra Braca , Josè Maria Prieto , Nunziatina De Tommasi , Franca Tomè , Ivano Morelli

DOI: 10.1016/J.PHYTOCHEM.2004.07.013

关键词:

摘要: Phytochemical analysis of the polar extracts leaves Helleborus viridis (Ranunculaceae) resulted in isolation two new furostanol saponins (25R)-26-[(alpha-L-rhamnopyranosyl)oxy]-22alpha-methoxyfurost-5-en-3beta-yl O-beta-D-glucopyranosyl-(1-->3)-O-[6-acetyl-beta-D-glucopyranosyl-(1-->3)]-O-beta-D-glucopyranoside (1) and O-beta-D-glucopyranosyl-(1-->3)-O-beta-D-glucopyranosyl-(1-->3)-O-beta-D-glucopyranoside (2) three quercetin glycosides, 3-O-(2-E-caffeoyl)-alpha-L-arabinopyranosyl-(1-->2)-beta-D-galactopyranoside-7-O-beta-d-glucopyranoside (3), 3-O-(2-E-caffeoyl)-alpha-L-arabinopyranosyl-(1-->2)-beta-D-galactopyranoside (4), 3-O-alpha-L-arabinopyranosyl-(1-->2)-beta-D-galactopyranoside (5). The structures compounds were determined by spectroscopic analysis, including 2D NMR data mass spectrometry.

参考文章(14)
Sandro Pignatti, Flora d'Italia (1982). ,vol. 1, ,(2017)
R. Tschesche, B.T. Tjoa, G. Wulff, R.V. Noronha, Steroidsaponine mit mehr als einer zuckerkette, III Tetrahedron Letters. ,vol. 9, pp. 5141- 5144 ,(1968) , 10.1016/S0040-4039(00)72304-5
Zhou Zhong Liang, Rita Aquino, Francesco De Simone, Antonio Dini, Oreste Schettino, Cosimo Pizza, None, Oligofurostanosides from Asparagus cochinchinensis. Planta Medica. ,vol. 54, pp. 344- 346 ,(1988) , 10.1055/S-2006-962453
M. L. Colombo, F. Tome', O. Servettaz, C. Bugatti, Phytochemical evaluation of Helleborus Species Growing in Northern Italy International Journal of Crude Drug Research. ,vol. 28, pp. 219- 223 ,(1990) , 10.3109/13880209009082817
Alessandra Braca, Ammar Bader, Ivano Morelli, Roberto Scarpato, Gino Turchi, Cosimo Pizza, Nunziatina De Tommasi, None, New pregnane glycosides from Caralluma negevensis Tetrahedron. ,vol. 58, pp. 5837- 5848 ,(2002) , 10.1016/S0040-4020(02)00563-X
A DEBELLA, E HASLINGER, O KUNERT, G MICHL, D ABEBE, Steroidal saponins from Asparagus africanus. Phytochemistry. ,vol. 51, pp. 1069- 1075 ,(1999) , 10.1016/S0031-9422(99)00051-5
Gelsomina Fico, Alessandra Braca, Nunziatina De Tommasi, Franca Tomè, Ivano Morelli, Flavonoids from Aconitum napellus subsp. neomontanum. Phytochemistry. ,vol. 57, pp. 543- 546 ,(2001) , 10.1016/S0031-9422(01)00102-9
Mei Dong, Xi-zhi Feng, Ben-xiang Wang, Li-jun Wu, Takashi Ikejima, Two novel furostanol saponins from the rhizomes of Dioscorea panthaica Prain et Burkill and their cytotoxic activity Tetrahedron. ,vol. 57, pp. 501- 506 ,(2001) , 10.1016/S0040-4020(00)01024-3
Laura Coassini Lokar, Livio Poldini, Herbal remedies in the traditional medicine of the Venezia Giulia Region (North East Italy) Journal of Ethnopharmacology. ,vol. 22, pp. 231- 279 ,(1988) , 10.1016/0378-8741(88)90238-3