Steroidal Saponins from Smilax medica and Their Antifungal Activity
作者： Marc Sautour , Tomofumi Miyamoto , Marie-Aleth Lacaille-Dubois
DOI: 10.1021/NP058060B
关键词:
摘要: Three new steroidal saponins (1−3) were isolated from the roots of Smilax medica, together with known disporoside A (4). The structures compounds elucidated mainly by extensive spectroscopic analysis (1D and 2D NMR, FABMS, HRESIMS). Compounds 1, 2, 4 demonstrated weak antifungal activity against human pathogenic yeasts Candida albicans, C. glabrata, tropicalis, MIC values between 12.5 50 μg/mL.
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