作者: B. Brett Finlay , Grant McFadden
DOI: 10.1016/J.CELL.2006.01.034
关键词:
摘要: Multicellular organisms possess very sophisticated defense mechanisms that are designed to effectively counter the continual microbial insult of environment within vertebrate host. However, successful pathogens have in turn evolved complex and efficient methods overcome innate adaptive immune mechanisms, which can result disease or chronic infections. Although various virulence strategies used by viral bacterial numerous, there several general subvert exploit systems shared between these diverse pathogens. The success each pathogen is directly dependant on its ability mount an effective anti-immune response infected host, ultimately acute disease, infection, clearance. In this review, we highlight compare some many molecular use evade host defenses.