Meniscus repair using mesenchymal stem cells - a comprehensive review.

作者: Hana Yu , Adetola B Adesida , Nadr M Jomha

DOI: 10.1186/S13287-015-0077-2

关键词:

摘要: The menisci are a pair of semilunar fibrocartilage structures that play an essential role in maintaining normal knee function. Injury to the can disrupt joint stability and lead debilitating results. Because natural meniscal healing is limited, efficient method repair necessary. Tissue engineering (TE) combines principles life sciences restore unique architecture native meniscus. Mesenchymal stem cells (MSCs) have been investigated for their therapeutic potential both vitro vivo. This comprehensive review examines English literature identified through database search using Medline, Embase, Engineering Village, SPORTDiscus. results were classified based on MSC type, animal model, delivery/culture. A variety types, including bone marrow-derived, synovium-derived, adipose-derived, meniscus-derived MSCs, has examined. Research categorized into discussed by different models used; namely murine, leporine, porcine, caprine, bovine, ovine, canine, equine, human meniscus defect/repair. Within each studies further according delivery/culture techniques. These techniques included direct application, fibrin glue/gel/clot, intra-articular injection, scaffold, tissue-engineered construct, tissue, pellets/aggregates, hydrogel. purpose this inform reader about current state advances TE MSCs. Future directions MSC-based also suggested help guide prospective research.

参考文章(96)
C Scotti, , MT Hirschmann, P Antinolfi, I Martin, GM Peretti, Meniscus repair and regeneration: review on current methods and research potential. European Cells & Materials. ,vol. 26, pp. 150- 170 ,(2013) , 10.22203/ECM.V026A11
John Kisiday, Cristin Keohan, Dan Busse, Christopher J Centeno, David Karli, Michael Freeman, Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells. Pain Physician. ,vol. 11, pp. 343- ,(2008)
William E. GarrettJr., American Board of Orthopaedic Surgery Practice of the Orthopaedic Surgeon: Part-II, certification examination case mix. Journal of Bone and Joint Surgery, American Volume. ,vol. 88, pp. 660- 667 ,(2006) , 10.2106/JBJS.E.01208
Makiko Okuno, Takeshi Muneta, Hideyuki Koga, Nobutake Ozeki, Yusuke Nakagawa, Kunikazu Tsuji, Shinichi Yoshiya, Ichiro Sekiya, Meniscus regeneration by syngeneic, minor mismatched, and major mismatched transplantation of synovial mesenchymal stem cells in a rat model Journal of Orthopaedic Research. ,vol. 32, pp. 928- 936 ,(2014) , 10.1002/JOR.22614
Daisuke Hatsushika, Takeshi Muneta, Masafumi Horie, Hideyuki Koga, Kunikazu Tsuji, Ichiro Sekiya, Intraarticular injection of synovial stem cells promotes meniscal regeneration in a rabbit massive meniscal defect model. Journal of Orthopaedic Research. ,vol. 31, pp. 1354- 1359 ,(2013) , 10.1002/JOR.22370
Mohammed Abdel-Hamid, Mahmoud R. Hussein, Ahmad F. Ahmad, Ebtisma M. Elgezawi, Enhancement of the repair of meniscal wounds in the red–white zone (middle third) by the injection of bone marrow cells in canine animal model International Journal of Experimental Pathology. ,vol. 86, pp. 117- 123 ,(2005) , 10.1111/J.0959-9673.2005.00420.X
Johannes Zellner, Katja Hierl, Michael Mueller, Christian Pfeifer, Arne Berner, Thomas Dienstknecht, Werner Krutsch, Sebastian Geis, Sebastian Gehmert, Richard Kujat, Sebastian Dendorfer, Lukas Prantl, Michael Nerlich, Peter Angele, Stem cell-based tissue-engineering for treatment of meniscal tears in the avascular zone. Journal of Biomedical Materials Research Part B. ,vol. 101, pp. 1133- 1142 ,(2013) , 10.1002/JBM.B.32922
Norah-Faye Matthies, Aillette Mulet-Sierra, Nadr M. Jomha, Adetola B. Adesida, Matrix formation is enhanced in co-cultures of human meniscus cells with bone marrow stromal cells. Journal of Tissue Engineering and Regenerative Medicine. ,vol. 7, pp. 965- 973 ,(2013) , 10.1002/TERM.1489
Tristan P. Driscoll, Nandan L. Nerurkar, Nathan T. Jacobs, Dawn M. Elliott, Robert L. Mauck, Fiber angle and aspect ratio influence the shear mechanics of oriented electrospun nanofibrous scaffolds. Journal of The Mechanical Behavior of Biomedical Materials. ,vol. 4, pp. 1627- 1636 ,(2011) , 10.1016/J.JMBBM.2011.03.022
Andrew Harston, John Nyland, Emily Brand, Mark McGinnis, David N. M. Caborn, Collagen meniscus implantation: a systematic review including rehabilitation and return to sports activity Knee Surgery, Sports Traumatology, Arthroscopy. ,vol. 20, pp. 135- 146 ,(2012) , 10.1007/S00167-011-1579-9