The tripeptide feG inhibits leukocyte adhesion.
作者： Ronald D Mathison , Emily Christie , Joseph S Davison
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摘要: Background The tripeptide feG (D-Phe-D-Glu-Gly) is a potent anti-inflammatory peptide that reduces the severity of type I immediate hypersensitivity reactions, and inhibits neutrophil chemotaxis adhesion to tissues. also expression β1-integrin on circulating neutrophils, but counter ligands involved in anti-adhesive actions are not known. In this study effects rat peritoneal leukocytes extravasated neutrophils several different integrin selective substrates were evaluated.
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