Brain Serotonin and Energy Homeostasis
作者： Pingwen Xu , Yanlin He , Yong Xu
DOI: 10.1016/B978-0-12-800050-2.00015-2
关键词:
摘要: Abstract 5-Hydroxytryptamine (5-HT, serotonin) in the brain regulates energy balance through different mechanisms. Identification and cloning of 5-HT receptors, pharmacology, genetic mouse models with 5-HT-receptor mutations have facilitated discoveries regarding complex effects signals on feeding behavior body weight balance. More importantly, some analogues are used clinically to treat obesity eating disorders. In this chapter we outlined (1) roles receptors regulation balance, (2) 5-HT–responsive neurocircuits that relevant for control, (3) drugs targeting treatment obesity.
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