作者: Marco Merlo , Anita Spezzacatene , Davide Stolfo , Francesca Brun , Gianfranco Sinagra
DOI: 10.1007/978-3-319-06019-4_4
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摘要: Idiopathic dilated cardiomyopathy (DCM) is a primary heart-muscle disease characterized by dilation and systolic dysfunction of the left or both ventricles. It represents frequent cause heart failure (HF) frequently deteriorates toward transplantation in relatively young patients. At least 30–50% cases are familial, suggesting relevant genetic involvement highlighting relevance on familial screening. Postmyocarditis other major DCM. affects mostly males during fourth fifth decades life, with low profile comorbidity. Despite impressive improvement knowledge, pharmacological/nonpharmacological treatments and, subsequently, prognosis this last 30 years, some critical issues remain challenging, such as prognostic stratification (particularly arrhythmic events more so than HF-related events). DCM an exclusion diagnosis when known causes excluded.