Detecting t(1;19)

作者: Robert B. Jenkins

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摘要: This document provides methods and materials related to detecting t(1;19) as well for identifying or assessing cancer within a mammal (e.g., human). For example, the aggressiveness of low-grade glioma in human are provided.

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Robert B. Jenkins, Hilary Blair, Karla V. Ballman, Caterina Giannini, Robert M. Arusell, Mark Law, Heather Flynn, Sandra Passe, Sara Felten, Paul D. Brown, Edward G. Shaw, Jan C. Buckner, A t(1;19)(q10;p10) Mediates the Combined Deletions of 1p and 19q and Predicts a Better Prognosis of Patients with Oligodendroglioma Cancer Research. ,vol. 66, pp. 9852- 9861 ,(2006) , 10.1158/0008-5472.CAN-06-1796
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Jan C. Buckner, Dean Gesme, Judith R. O’Fallon, Julie E. Hammack, Scott Stafford, Paul D. Brown, Roland Hawkins, Bernd W. Scheithauer, Bradley J. Erickson, Ralph Levitt, Edward G. Shaw, Robert Jenkins, Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. Journal of Clinical Oncology. ,vol. 21, pp. 251- 255 ,(2003) , 10.1200/JCO.2003.06.023
Justin S. Smith, Arie Perry, Thomas J. Borell, Hyun K. Lee, Judith O’Fallon, Sandra M. Hosek, David Kimmel, Allan Yates, Peter C. Burger, Bernd W. Scheithauer, Robert B. Jenkins, Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas Journal of Clinical Oncology. ,vol. 18, pp. 636- 645 ,(2000) , 10.1200/JCO.2000.18.3.636
Karla V. Ballman, Ken Aldape, Jan C. Buckner, Robert B. Jenkins, Caterina Giannini, Mark Law, Hilary Blair, Heather Flynn, Sandra Passe, Histone deacetylase inhibitors (HDACIs) induce HIF-1 transcriptional activity. Cancer Research. ,vol. 66, pp. 1348- 1348 ,(2006)