Role of N-Cadherin in Intercellular Adhesion, Tissue Development, Cytoskeleton Formation, and Signaling
作者： Megan L. Sierant , John D. Bartlett
DOI: 10.1007/978-4-431-54070-0_112
关键词:
摘要: N-cadherin is a classical member of the cadherin super-family. Classical cadherins are transmembrane glycoproteins that mediate calcium-dependent homophilic protein–protein interaction for cell–cell adhesion and signaling. component adherens junction mice with ablated from their genome die during early gestation. also involved in several signaling pathways may regulate cell differentiation motility. Therefore, critical normal development it play role enamel formation because ameloblast cells responsible express developmentally defined manner.
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