Noninvasive long-term ventilatory support for individuals with spinal muscular atrophy and functional bulbar musculature

摘要: Abstract Ten individuals with spinal muscular atrophy (SMA) and chronic ventilatory insufficiency were trained in the use of assisted coughing techniques received intermittent positive pressure ventilation (IPPV) via oral and/ or nasal interfaces for a mean 5.3 (range = 1 to 17) years. During this time they had significantly fewer respiratory complications than before introduction noninvasive muscle aids despite fact that 6 10 went on require more 20 hours per day ventilator less 2 ventilator-free breathing (VFBT). All except two IPPV users vital capacities (VCs) 13% predicted normal. They could, however, communicate verbally take nutrition by mouth. patients remained community. Five gainfully employed four school. We conclude including are effective practical alternatives tracheostomy SMA failure but functional bulbar musculature.