Pharmacometabonomics in humans: a new tool for personalized medicine.

摘要: Pharmacogenomics is now over 50 years old and has had some impact in clinical practice, through its use to select patient subgroups who will enjoy efficacy without side effects when treated with certain drugs. However, pharmacogenomics, less than initially predicted. One reason for this that many diseases, the way which patients respond drug treatments, have both genetic environmental elements. Pure genomics almost blind A new methodology emerged, termed pharmacometabonomics concerned prediction of analysis predose, biofluid metabolite profiles, reflect influences on human physiology. In review we cover what is, how it works, applications exist future might hold exciting area.