Serine 518 phosphorylation modulates merlin intramolecular association and binding to critical effectors important for NF2 growth suppression.

作者: Rong Rong , Ezequiel I Surace , Carrie A Haipek , David H Gutmann , Keqiang Ye

DOI: 10.1038/SJ.ONC.1207794

关键词:

摘要: The neurofibromatosis 2 (NF2) tumor suppressor protein, merlin, functions as a negative growth regulator; however, the molecular mechanisms that underlie merlin regulation remain …

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