作者: R.E. Sinden
DOI: 10.1016/BS.APAR.2016.09.004
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摘要: This article attempts to draw together current knowledge on the biology of Plasmodium and experience gained from past control campaigns interpret guide efforts discover develop exciting new strategies targeting parasite with objective interrupting transmission. Particular note is made advantages often unappreciated small, yet vital, bottleneck populations enhance both impact useful lifetime hard-won interventions. A case for standardization methods measure transmission blockade permit rational comparison how diverse interventions (drugs, vaccines, insecticides, Genetically Modified technologies) disparate aspects may upon commonly used parameter prevalence in human population.