Network analysis of DEGs and verification experiments reveal the notable roles of PTTG1 and MMP9 in lung cancer
作者： Xiaohui Xu , Lei Cao , Ye Zhang , Yan Yin , Xue Hu
DOI: 10.3892/OL.2017.7329
关键词:
摘要: … In summary, PTTG1 and MMP9 were identified as … of DEGs in lung cancer tissues was performed, then the protein interaction and transcriptional regulatory networks were identified and …
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Gabriele Bergers, Rolf Brekken, Gerald McMahon, Thiennu H. Vu, Takeshi Itoh, Kazuhiko Tamaki, Kazuhiko Tanzawa, Philip Thorpe, Shigeyoshi Itohara, Zena Werb, Douglas Hanahan, Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis Nature Cell Biology. ,vol. 2, pp. 737- 744 ,(2000) , 10.1038/35036374
Meijun Lv, Lishan Wang, Comprehensive analysis of genes, pathways, and TFs in nonsmoking Taiwan females with lung cancer Experimental Lung Research. ,vol. 41, pp. 74- 83 ,(2015) , 10.3109/01902148.2014.971472
Yi-Ming MU, Koichi OBA, Toshihiko YANASE, Takeshi ITO, Kenji ASHIDA, Kiminobu GOTO, Hidetaka MORINAGA, Shoichiro IKUYAMA, Ryoichi TAKAYANAGI, Hajime NAWATA, Human pituitary tumor transforming gene (hPTTG) inhibits human lung cancer A549 cell growth through activation of p21(WAF1/CIP1 ) Endocrine Journal. ,vol. 50, pp. 771- 781 ,(2003) , 10.1507/ENDOCRJ.50.771
Ching-Wu Hsia, Ming-Yi Ho, Hao-Ai Shui, Chong-Bin Tsai, Min-Jen Tseng, Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine International Journal of Molecular Sciences. ,vol. 16, pp. 3579- 3598 ,(2015) , 10.3390/IJMS16023579
David G. Beer, Sharon L.R. Kardia, Chiang-Ching Huang, Thomas J. Giordano, Albert M. Levin, David E. Misek, Lin Lin, Guoan Chen, Tarek G. Gharib, Dafydd G. Thomas, Michelle L. Lizyness, Rork Kuick, Satoru Hayasaka, Jeremy M.G. Taylor, Mark D. Iannettoni, Mark B. Orringer, Samir Hanash, Gene-expression profiles predict survival of patients with lung adenocarcinoma Nature Medicine. ,vol. 8, pp. 816- 824 ,(2002) , 10.1038/NM733
Piroon Jenjaroenpun, Vladimir A Kuznetsov, TTS Mapping: integrative WEB tool for analysis of triplex formation target DNA Sequences, G-quadruplets and non-protein coding regulatory DNA elements in the human genome BMC Genomics. ,vol. 10, pp. 1- 18 ,(2009) , 10.1186/1471-2164-10-S3-S9
C. J. McCabe, J. S. Khaira, K. Boelaert, A. P. Heaney, L. A. Tannahill, S. Hussain, R. Mitchell, J. Olliff, M. C. Sheppard, J. A. Franklyn, N. J. L. Gittoes, Expression of pituitary tumour transforming gene (PTTG) and fibroblast growth factor-2 (FGF-2) in human pituitary adenomas: relationships to clinical tumour behaviour Clinical Endocrinology. ,vol. 58, pp. 141- 150 ,(2003) , 10.1046/J.1365-2265.2003.01598.X
William D Travis, Pathology of lung cancer. Clinics in Chest Medicine. ,vol. 23, pp. 65- 81 ,(2002) , 10.1016/S0272-5231(03)00061-3
Lin Li, Jinjing Tan, Ying Zhang, Naijun Han, Xuebing Di, Ting Xiao, Shujun Cheng, Yanning Gao, Yu Liu, DLK1 Promotes Lung Cancer Cell Invasion through Upregulation of MMP9 Expression Depending on Notch Signaling PLoS ONE. ,vol. 9, pp. e91509- ,(2014) , 10.1371/JOURNAL.PONE.0091509
J. W. Kim, J. Y. Song, J. M. Lee, J. K. Lee, N. W. Lee, B. W. Yeom, K. W. Lee, Expression of pituitary tumor-transforming gene in endometrial cancer as a prognostic marker. International Journal of Gynecological Cancer. ,vol. 18, pp. 1352- 1359 ,(2008) , 10.1111/J.1525-1438.2007.01168.X