Loss of ARID1A Expression in Gastric Cancer: Correlation with Mismatch Repair Deficiency and Clinicopathologic Features.

作者: Kyung-Ju Kim , Hae Yoen Jung , Mee-Hye Oh , Hyundeuk Cho , Ji-Hye Lee

DOI: 10.5230/JGC.2015.15.3.201

关键词:

摘要: Purpose The AT-rich interactive domain 1A (ARID1A) gene encodes BRG1-associated factor 250a, a component of the SWItch/Sucrose NonFermentable chromatin remodeling complex, which is considered tumor suppressor in many tumors. We aimed to investigate prognostic significance ARID1A expression gastric cancers and explore its relationship with clinicopathologic parameters such as mismatch repair protein expression.

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