Biomedical modification of poly(L-lactide) by blending with lecithin.

作者: N. Zhu , F.Z. Cui , K. Hu , L. Zhu

DOI: 10.1002/JBM.A.31159

关键词:

摘要: Lecithin was, for the first time, blended with PLLA to prepare scaffold material tissue engineering applications in present study. Solution blending was used incorporate (containing 0–10 wt %) enhance blend films biocompatibility, hydrophilicity and toughness while maintaining mechanical strength of PLLA. The results FTIR-ATR analysis indicated that amino groups lecitin existed films. DSC Tg decreased increase lecithin content percentage elongation markedly increased content. proliferation viability vascular smooth muscle cell cultures on PLLA/Lecithin 3–7 were significantly enhanced compared pure culture plates. © 2007 Wiley Periodicals, Inc. J Biomed Mater Res,

参考文章(30)
G.R.D. Evans, K. Brandt, M.S. Widmer, L. Lu, R.K. Meszlenyi, P.K. Gupta, A.G. Mikos, J. Hodges, J. Williams, A. Gürlek, A. Nabawi, R. Lohman, C.W. Patrick, In vivo evaluation of poly(L-lactic acid) porous conduits for peripheral nerve regeneration. Biomaterials. ,vol. 20, pp. 1109- 1115 ,(1999) , 10.1016/S0142-9612(99)00010-1
Suming Li, Stephen McCarthy, Further investigations on the hydrolytic degradation of poly (DL-lactide) Biomaterials. ,vol. 20, pp. 35- 44 ,(1999) , 10.1016/S0142-9612(97)00226-3
K. Walachová, V. Švorčı́k, L. Bačáková, V. Hnatowicz, Colonization of ion-modified polyethylene with vascular smooth muscle cells in vitro. Biomaterials. ,vol. 23, pp. 2989- 2996 ,(2002) , 10.1016/S0142-9612(02)00029-7
R.M. Shelton, A.C. Rasmussen, J.E. Davies, Protein adsorption at the interface between charged polymer substrata and migrating osteoblasts Biomaterials. ,vol. 9, pp. 24- 29 ,(1988) , 10.1016/0142-9612(88)90065-8
Antonios G. Mikos, Michelle D. Lyman, Lisa E. Freed, Robert Langer, Wetting of poly(L-lactic acid) and poly(DL-lactic-co-glycolic acid) foams for tissue culture. Biomaterials. ,vol. 15, pp. 55- 58 ,(1994) , 10.1016/0142-9612(94)90197-X
M. Sittinger, D. Reitzel, M. Dauner, H. Hierlemann, C. Hammer, E. Kastenbauer, H. Planck, G. R. Burmester, J. Bujia, Resorbable polyesters in cartilage engineering: Affinity and biocompatibility of polymer fiber structures to chondrocytes Journal of Biomedical Materials Research. ,vol. 33, pp. 57- 63 ,(1996) , 10.1002/(SICI)1097-4636(199622)33:2<57::AID-JBM1>3.0.CO;2-K
Jin Ho Lee, Gilson Khang, Jin Whan Lee, Hai Bang Lee, None, Interaction of Different Types of Cells on Polymer Surfaces with Wettability Gradient Journal of Colloid and Interface Science. ,vol. 205, pp. 323- 330 ,(1998) , 10.1006/JCIS.1998.5688
P.B van Wachem, A.H Hogt, T Beugeling, J Feijen, A Bantjes, J.P Detmers, W.G van Aken, Adhesion of cultured human endothelial cells onto methacrylate polymers with varying surface wettability and charge Biomaterials. ,vol. 8, pp. 323- 328 ,(1987) , 10.1016/0142-9612(87)90001-9
Z. Kulinski, E. Piorkowska, Crystallization, structure and properties of plasticized poly(l-lactide) Polymer. ,vol. 46, pp. 10290- 10300 ,(2005) , 10.1016/J.POLYMER.2005.07.101
Margaret D. M. Evans, John G. Steele, Polymer surface chemistry and a novel attachment mechanism in corneal epithelial cells. Journal of Biomedical Materials Research. ,vol. 40, pp. 621- 630 ,(1998) , 10.1002/(SICI)1097-4636(19980615)40:4<621::AID-JBM14>3.0.CO;2-I