Hyaluronic Acid-Based Medical Device for Treatment of Alveolar Osteitis-Clinical Study.

摘要: Alveolar Osteitis (AO) is a complication following the extraction of tooth. AO manifests through localized pain in, and around, site, where post-operative blood clot has been disintegrated. The aim this single cohort study was to evaluate outcome treatment AO, using pharmacological device composed hyaluronic acid octenidine dihydrochloride. tested sponge-like material, solely fully dissoluble medicaments (hyaluronic acid, calcium chloride, dihydrochloride). It designed serve as non-toxic, slow-dissolving antiseptic, that adheres mucosa obturates wound. This includes 58 subjects who were diagnosed with AO. administered once daily until local subsided < 20 mm Visual Analog Scale (VAS). considered effective when VAS in 8 days treatment; per comparative studies. Our findings provide statistically significant success rate 96.0% (95.0% confidence interval 75.75% 97.8%) after administrations. No adverse medical effects detected. Acquired data confirmed lyophilized combined octenidine, for results are clinically important common third molar extractions.