Analysis of Intron Sequence Features Associated with Transcriptional Regulation in Human Genes
作者： Huimin Li , Dan Chen , Jing Zhang
DOI: 10.1371/JOURNAL.PONE.0046784
关键词:
摘要: Although some preliminary work has revealed the potential transcriptional regulatory function of introns in eukaryotes, additional evidences are needed to support this conjecture. In study, we perform systemic analyses sequence characteristics human introns. The results show that first generally longer and C, G their dinucleotide compositions over-represented relative other introns, which consistent with previous findings. addition, new phenomena concerned regulation found: i) enriched CpG islands; ii) percentages containing TATA, CAAT GC boxes relatively higher than position similar features observed tissue-specific genes. further genes likely be involved regulation, give an insight into regions
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core.ac.uk 参考文章(34)
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