Usefulness of antimicrobial susceptibility in the eradication of Helicobacter pylori
作者： A. Cosme , M. Montes , M. Martos , I. Gil , U. Mendarte
DOI: 10.1111/J.1469-0691.2012.03844.X
关键词:
摘要: The rate of eradication Helicobacter pylori with standard triple therapy using omeprazole, amoxicillin and clarithromycin (OAC) is unacceptable in populations high rates resistance (15-20%). aim this study was to compare the efficacy 10-day OAC as first-line treatment patients diagnosed by culture antimicrobial susceptibility or a (13) C-labelled urea breath test (UBT) without an area where 15-20%. This retrospective cohort 266 patients, recruited consecutively throughout 2008. A total 247 H. pylori-infected received antibiotic (221 26 other regimens) which 134 were gastric samples followed testing 113 UBT. In all checked cost assessed each patient. success UBT 88% (103/117) 49% (51/104), respectively (p <0.0005). also more cost-effective former these two groups (€571 versus €666). To perform isolates successful effective strategy than empirical clarithromycin.
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