A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding
作者： John B. Mangrum , Brigitte J. Engelmann , Erica J. Peterson , John J. Ryan , Susan J. Berners-Price
DOI: 10.1039/C3CC49695C
关键词:
摘要: Metalloglycomics – the effects of defined coordination compounds on oligosaccharides and their structure function opens new areas for bioinorganic chemistry expands its systematic study to third major class biomolecules after DNA/RNA proteins.
rsc.org
core.ac.uk
sci-hub.se 参考文章(24)
John B. Mangrum, Nicholas P. Farrell, Excursions in polynuclear platinum DNA binding Chemical Communications. ,vol. 46, pp. 6640- 6650 ,(2010) , 10.1039/C0CC01254H
Neha S. Gandhi, Ricardo L. Mancera, The Structure of Glycosaminoglycans and their Interactions with Proteins Chemical Biology & Drug Design. ,vol. 72, pp. 455- 482 ,(2008) , 10.1111/J.1747-0285.2008.00741.X
Rasha A. Ruhayel, Ben Corry, Carlos Braun, Donald S. Thomas, Susan J. Berners-Price, Nicholas P. Farrell, Determination of the Kinetic Profile of a Dinuclear Platinum Anticancer Complex in the Presence of Sulfate: Introducing a New Tool for the Expedited Analysis of 2D [1H, 15N] HSQC NMR Spectra Inorganic Chemistry. ,vol. 49, pp. 10815- 10819 ,(2010) , 10.1021/IC100576K
Edward Hammond, Cai Ping Li, Vito Ferro, Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening Analytical Biochemistry. ,vol. 396, pp. 112- 116 ,(2010) , 10.1016/J.AB.2009.09.007
Flonia Levy-Adam, Neta Ilan, Israel Vlodavsky, Tumorigenic and adhesive properties of heparanase. Seminars in Cancer Biology. ,vol. 20, pp. 153- 160 ,(2010) , 10.1016/J.SEMCANCER.2010.06.005
Youjin Seo, Matthew R. Schenauer, Julie A. Leary, Biologically relevant metal-cation binding induces conformational changes in heparin oligosaccharides as measured by ion mobility mass spectrometry International Journal of Mass Spectrometry. ,vol. 303, pp. 191- 198 ,(2011) , 10.1016/J.IJMS.2011.02.003
Heveline Silva, Frédéric Frézard, Erica J. Peterson, Peyman Kabolizadeh, John J. Ryan, Nicholas P. Farrell, Heparan sulfate proteoglycan-mediated entry pathway for charged tri-platinum compounds: differential cellular accumulation mechanisms for platinum. Molecular Pharmaceutics. ,vol. 9, pp. 1795- 1802 ,(2012) , 10.1021/MP300098T
Seiji Komeda, Tinoush Moulaei, Masahiko Chikuma, Akira Odani, Ralph Kipping, Nicholas P. Farrell, Loren Dean Williams, The phosphate clamp: a small and independent motif for nucleic acid backbone recognition Nucleic Acids Research. ,vol. 39, pp. 325- 336 ,(2011) , 10.1093/NAR/GKQ723
Mark M. Fuster, Jeffrey D. Esko, The sweet and sour of cancer: glycans as novel therapeutic targets. Nature Reviews Cancer. ,vol. 5, pp. 526- 542 ,(2005) , 10.1038/NRC1649
Israel Vlodavsky, Orit Goldshmidt, Eyal Zcharia, Ruth Atzmon, Zehava Rangini-Guatta, Michael Elkin, Tamar Peretz, Yael Friedmann, Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development. Seminars in Cancer Biology. ,vol. 12, pp. 121- 129 ,(2002) , 10.1006/SCBI.2001.0420