The effect of iron deficiency and iron overload on the evolution of chagas disease produced by three strains of Trypanosoma cruzi in CFW mice

作者: Maria Lucia Pedrosa , Marcelo E Sllva , Márcio E Silva , M.E.C Silva , J.R Nicoli

DOI: 10.1016/0300-9629(90)90178-U

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摘要: Abstract 1. CFW mice were fed either on control diet or iron-deficient diet. 2. After 5 months the infected with CL, Y YuYu strain of Trypanosoma cruzi . 3. On fifth day after infection, divided in three groups: one group remained as controls, two groups injected desferrioxamine iron-dextran. 4. The severity disease was evaluated by parasitemia and mortality. 5. experimental compared 6. In diet, more severe for CL less strains. 7. Treatment produced a no difference other 8. treatment iron-dextran, became strains; effect observed strain. 9. These findings may be due to intraspecific differences among

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