Late biliary obstruction in Wistar rats after intermittent hepatic pedicle clamping.
作者： G.d.L. Jorge , R.d.R. Tártaro , A.C.C. Facin , R.A.T. Pereira , C.A.F. Escanhoela
DOI: 10.1016/J.TRANSPROCEED.2014.05.067
关键词:
摘要: Abstract Introduction The temporary vascular occlusion of hepatic flow is one the essential procedures in surgery. Aim Evaluate late liver alterations after intermittent pedicle clamping (IHPC) Wistar rats. Methods Male rats (n = 14) with average weight 281.1 g, were anesthetized intraperitoneal ketamine 5%. IHPC group 7) was submitted to U-shaped abdominal incision; isolated and ischemia 4 times, 5 minutes each, followed by reperfusion each. simulated operation subjected anesthesia, laparotomy, manipulation pedicle. On day 35, fasting for 12 hours, biopsies collected blood tested aminotransferases (aspartate aminotransferase/alanine aminotransferase). Results All animals had a dilated common bile duct increased enzymes (P Conclusion In rats, caused morphologic features leading biliary obstruction.
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