Low prevalence of vitamin D deficiency in elderly Afro-Caribbean men.

摘要: Vitamin D deficiency is highly prevalent worldwide, and linked to several major chronic, inflammatory autoimmune diseases. has not been evaluated in dark skinned individuals living areas of high sun exposure utilizing more reliable mass spectrometry assay techniques. We determined the prevalence 25-hydroxyvitamin (25(OH)D) Afro-Caribbean men on tropical island Tobago, where there a level sunshine year round. Serum 25(OH)D2 25(OH)D3 metabolites were measured following extraction purification using liquid chromatography tandem 424 aged .65 years from larger population-based cohort study. The mean (6SD) serum total 25(OH)D concentration was 35.1 6 8.9 ng/mL. Deficiency (,20 ng/mL) present only 2.8% insufficiency (,30 24% men. Multiple linear regression analysis identified age, BMI daily vitamin supplementation as independent correlates 25(OH)D. None who consumed fish than once per week had deficiency, compared 4% or less (P5.01, adjusted for BMI, supplementation). In conclusion, very uncommon this population. Longitudinal studies are needed delineate possible effects levels population diseases hypothesized be associated with deficiency. (Ethn Dis. 2011;21:79–84)