Increased frequency of X-bearing sperm in males from an infertility clinic: analysis by two-color fluorescence in situ hybridization

摘要: Semen samples from 34 men visiting the Lubeck infertility clinic were investigated using a two-color FISH method to determine ratio of X- and Y-bearing sperm. The overall was significantly shifted preponderance X-containing A statistical comparison with seven reports literature which included 53 normal probands demonstrated in our patients significant tendency X-bearing sperm less Furthermore, are remarkably more heterogeneous respect their variability spermatozoa than other mentioned studies probands. These phenomena have be evaluated further on groups infertile males showing similar histories.