Evaluation of hemostaseological status of pigs experimentally infected with African swine fever virus.

摘要: African swine fever is a highly contagious hemorrhagic disease of pigs caused by virus (ASFV). Hemorrhages are the most frequently reported lesions in acute and subacute forms ASF. Hemorrhagic accompanied impaired hemostasis, which includes thrombocytopenia changes coagulation system. In present study, experimental infection was conducted to elucidate whether virulent ASFV genotype II circulating Trans-Caucasus Eastern Europe affects hemostasis infected pigs. Platelet count platelet size, as well parameters were evaluated upon infection. contrast other strains, showed significant decrease number platelets from 3rd dpi onwards. Furthermore, size observed throughout entire period experiment. A increase aggregates beginning Unlike induced slight shortening an activated partial thromboplastin time (aPTT) Thrombin (TT) prolonged day 5 onwards, whereas no prothrombin (PT) found The level d-dimers permanently higher than control with peak on 3 post-infection. fibrinogen till end Thus, it can be concluded that isolated Armenia causes differ strains described previously.