Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Rheumatoid Arthritis

摘要: Nonsteroidal anti-inflammatory drugs (NSAIDs) continue to be a mainstay of rheumatoid arthritis (RA) management despite exciting recent advances in the therapy RA (Table 1). Before era modern medicine, willow bark, which contains salicylates, was used treat fever and pain (1). In 1860, salicylic acid introduced for treatment rheumatic diseases, followed by introduction acetylsalicylic (aspirin) 1899 Salicylates remained principle pharmacologic until glucocorticoids 1940s. current early, aggressive with disease modifying anti-rheumatic drugs, NSAIDs have assumed an adjunctive role reducing symptoms RA.