Populations of smooth muscle cells of specific embryonic lineages
作者： Andreia Bernardo , Christine Cheung , Roger Pedersen , Sanjay Sinha
DOI:
关键词:
摘要: This invention relates to the production of populations Smooth Muscle Cells (SMCs) specific embryonic lineages, such as neuroectodermal and mesodermal SMCs. Pluripotent stem cells are cultured in one or more lineage induction media produce progenitor a defined lineage, which then an SMC medium population SMCs lineage. Populations lineages may be useful, for example, accurately modelling vascular disease.
lens.org 参考文章(18)
Maureen Wanjare, Sharon Gerecht, Donny Hanjaya-Putra, Elaine Tuong Vi Vo, SMOOTH MUSCLE-LIKE CELLS (SMLCs) DERIVED FROM HUMAN PLURIPOTENT STEM CELLS ,(2011)
I. Gabrielle M. Brons, Ludovic Vallier, Roger Pedersen, Pluripotent cells from the mammalian late epiblast layer ,(2007)
Ludovic Vallier, Roger Pedersen, Differentiation of pluripotent cells into primary germ layer progenitors ,(2007)
Ilyas Singec, Evan Snyder, Directed differentiation of stem cells ,(2010)
Sharon Gerecht-Nir, Joseph Itskovitz-Eldor, Novel methods for the in-vitro identification, isolation and differentiation of vasculogenic progenitor cells ,(2003)
Sang-Wook Park, Yong-Mahn Han, Eun-young Lee, Method of inducing differentiation of embryonic stem cells into hemangioblast US. ,(2010)
Steven Kattman, Gordon M. Keller, Lei Yang, Human cardiovascular progenitor cells ,(2009)
Mark W. Majesky, Developmental Basis of Vascular Smooth Muscle Diversity Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 27, pp. 1248- 1258 ,(2007) , 10.1161/ATVBAHA.107.141069
Helena Vazão, Ricardo Pires das Neves, Mário Grãos, Lino Ferreira, Towards the maturation and characterization of smooth muscle cells derived from human embryonic stem cells. PLOS ONE. ,vol. 6, ,(2011) , 10.1371/JOURNAL.PONE.0017771
Jeffrey J Ross, Zhigang Hong, Ben Willenbring, Lepeng Zeng, Brett Isenberg, Eu Han Lee, Morayma Reyes, Susan A Keirstead, E Kenneth Weir, Robert T Tranquillo, Catherine M Verfaillie, None, Cytokine-induced differentiation of multipotent adult progenitor cells into functional smooth muscle cells Journal of Clinical Investigation. ,vol. 116, pp. 3139- 3149 ,(2006) , 10.1172/JCI28184