Effects of Graft Thickness and Asymmetry on Visual Gain and Aberrations After Descemet Stripping Automated Endothelial Keratoplasty

摘要: Importance Understanding the contribution of graft thickness and asymmetry to visual gain posterior corneal (PC) higher-order aberrations (HOAs) may assist optimizing outcomes after Descemet stripping automated endothelial keratoplasty (DSAEK). Objective To investigate effects on DSAEK. Design Retrospective analysis an interventional case series eyes undergoing Visual was defined as difference between preoperative 6-month postoperative best-corrected acuity in logMAR equivalents. Graft measured by anterior-segment optical coherence tomography. Corneal topography HOAs were Scheimpflug imaging. Raw elevation data exported fitted against a best-fitted sphere, providing measure donor lenticule asymmetry. Correlation performed among gain, thickness, asymmetry, PC HOAs. Setting University Eye Clinic Maastricht. Participants Seventy-nine with dysfunction. Exposure All patients underwent Main Outcomes Measures Results Mean improved from 0.63 equivalents preoperatively 0.25 postoperatively (P  Conclusions Relevance After DSAEK, shows significant correlation without vision-limiting comorbidities. This relationship is strongest pseudophakic bullous keratopathy. also correlates which turn all but spherical These findings surgeons choosing DSAEK shape, particularly Further randomized trials are needed