Heterogeneous Selective Pressure Acting on Influenza B Victoria- and Yamagata-Like Hemagglutinins

作者: Baltazar Nunes , Pedro Pechirra , Anabela Coelho , Carlos Ribeiro , Ana Arraiolos

DOI: 10.1007/S00239-008-9154-9

关键词:

摘要: As a consequence of immune pressure, influenza virus hemagglutinin presents some its amino acids under positive selection. Several authors have reported the existence A codons selective pressure (PSP). In this framework, present work objectives were to demonstrate presence PSP and evaluate effects on Victoria- Yamagata-like B viruses. Methodology adopted consisted in estimating acceptance rate nonsynonymous substitutions (ω = dN/dS) that describe strength identifying may be positively selected, applying set continuous-time Markov chain codon-substitution models. Two groups HA1 sequences (140 from Yamagata 60 Victoria lineage) used. All model maximum-likelihood estimates obtained using codeml software application (PAML 3.15). The hypothesis no sites was rejected for both lineages (p 0.95 197 199 lineages, codon 75 lineage, 129 lineage. detected are located at or near antigenic H3 hemagglutinin.

参考文章(45)
Robert A Lamb, Griffith D. Parks, Griffith D. Parks, Griffith D. Parks, Orthomyxoviridae: The Viruses and Their Replication. Fields virology. ,vol. 2, pp. 1449- 1496 ,(1996)
JP Bielawski, Z Yang, M Anisimova, The accuracy and power of likelihood ratio tests to detect positive selection at amino acid sites Molecular Biology and Evolution , 18 pp. 1585-1592. (2001). ,(2001)
Jonathan A. McCullers, George C. Wang, Shiqin He, Robert G. Webster, Reassortment and Insertion-Deletion Are Strategies for the Evolution of Influenza B Viruses in Nature Journal of Virology. ,vol. 73, pp. 7343- 7348 ,(1999) , 10.1128/JVI.73.9.7343-7348.1999
W. M. Fitch, R. M. Bush, C. A. Bender, N. J. Cox, Long term trends in the evolution of H(3) HA1 human influenza type A Proceedings of the National Academy of Sciences of the United States of America. ,vol. 94, pp. 7712- 7718 ,(1997) , 10.1073/PNAS.94.15.7712
Paul A. Rota, Teresa R. Wallis, Maurice W. Harmon, Jennifer S. Rota, Alan P. Kendal, Kuniaki Nerome, Cocirculation of two distinct evolutionary lineages of influenza type B virus since 1983. Virology. ,vol. 175, pp. 59- 68 ,(1990) , 10.1016/0042-6822(90)90186-U
J. W. Thomas, J. W. Touchman, R. W. Blakesley, G. G. Bouffard, S. M. Beckstrom-Sternberg, E. H. Margulies, M. Blanchette, A. C. Siepel, P. J. Thomas, J. C. McDowell, B. Maskeri, N. F. Hansen, M. S. Schwartz, R. J. Weber, W. J. Kent, D. Karolchik, T. C. Bruen, R. Bevan, D. J. Cutler, S. Schwartz, L. Elnitski, J. R. Idol, A. B. Prasad, S.-Q. Lee-Lin, V. V. B. Maduro, T. J. Summers, M. E. Portnoy, N. L. Dietrich, N. Akhter, K. Ayele, B. Benjamin, K. Cariaga, C. P. Brinkley, S. Y. Brooks, S. Granite, X. Guan, J. Gupta, P. Haghighi, S.-L. Ho, M. C. Huang, E. Karlins, P. L. Laric, R. Legaspi, M. J. Lim, Q. L. Maduro, C. A. Masiello, S. D. Mastrian, J. C. McCloskey, R. Pearson, S. Stantripop, E. E. Tiongson, J. T. Tran, C. Tsurgeon, J. L. Vogt, M. A. Walker, K. D. Wetherby, L. S. Wiggins, A. C. Young, L.-H. Zhang, K. Osoegawa, B. Zhu, B. Zhao, C. L. Shu, P. J. De Jong, C. E. Lawrence, A. F. Smit, A. Chakravarti, D. Haussler, P. Green, W. Miller, E. D. Green, Comparative analyses of multi-species sequences from targeted genomic regions Nature. ,vol. 424, pp. 788- 793 ,(2003) , 10.1038/NATURE01858
Makoto Yamashita, Mark Krystal, Walter M. Fitch, Peter Palese, Influenza B virus evolution: Co-circulating lineages and comparison of evolutionary pattern with those of influenza A and C viruses Virology. ,vol. 163, pp. 112- 122 ,(1988) , 10.1016/0042-6822(88)90238-3
Rasmus Nielsen, Carlos Bustamante, Andrew G Clark, Stephen Glanowski, Timothy B Sackton, Melissa J Hubisz, Adi Fledel-Alon, David M Tanenbaum, Daniel Civello, Thomas J White, John J. Sninsky, Mark D Adams, Michele Cargill, A Scan for Positively Selected Genes in the Genomes of Humans and Chimpanzees PLOS Biology. ,vol. 3, pp. 976- 985 ,(2005) , 10.1371/JOURNAL.PBIO.0030170
G. M. Air, A. J. Gibbs, W. G. Laver, R. G. Webster, Evolutionary changes in influenza B are not primarily governed by antibody selection. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 87, pp. 3884- 3888 ,(1990) , 10.1073/PNAS.87.10.3884