The blood-brain barrier and its role in immune privilege in the central nervous system.

作者: Joel S. Pachter , Helga E. de Vries , Zsuzsa Fabry

DOI: 10.1093/JNEN/62.6.593

关键词:

摘要: … blood-brain barrier (BBB) provides both anatomical and physiological protection for the central nervous system (… cells can create a predominantly proinflammatory local environment in …

参考文章(106)
D Male, G Pryce, J Sedgwick, Antigen presentation in brain: brain endothelial cells are poor stimulators of T-cell proliferation. Immunology. ,vol. 66, pp. 207- 212 ,(1989)
D Male, G Pryce, Kinetics of MHC gene expression and mRNA synthesis in brain endothelium. Immunology. ,vol. 63, pp. 37- 42 ,(1988)
Hugh Davson, History of the Blood-Brain Barrier Concept Springer, Boston, MA. pp. 27- 52 ,(1989) , 10.1007/978-1-4613-0701-3_2
Colin R. F. Monks, Benjamin A. Freiberg, Hannah Kupfer, Noah Sciaky, Abraham Kupfer, Three-dimensional segregation of supramolecular activation clusters in T cells Nature. ,vol. 395, pp. 82- 86 ,(1998) , 10.1038/25764
T F Gajewski, M M Waldschmidt, R G Lynch, M N Hart, Z Fabry, M Sandor, J A Herlein, Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes. Journal of Immunology. ,vol. 151, pp. 38- 47 ,(1993)
D. J. Topham, D. Fee, Z. Fabry, J. A. Carlino, M. N. Hart, Subramaniam Sriram, J. Herlein, TGF-beta 2 decreases migration of lymphocytes in vitro and homing of cells into the central nervous system in vivo. Journal of Immunology. ,vol. 155, pp. 325- 332 ,(1995)
H K Huynh, K Dorovini-Zis, Effects of interferon-gamma on primary cultures of human brain microvessel endothelial cells. American Journal of Pathology. ,vol. 142, pp. 1265- 1278 ,(1993)