Signal transduction: implications for Ras-dependent ERK signaling.
作者： Stéphane Ory , Deborah K. Morrison
DOI: 10.1016/J.CUB.2004.03.023
关键词:
摘要: Ras interacts with numerous downstream effectors to transmit a diverse array of cellular signals. A new study shows that protein known as Impedes Mitogenic signal Propagation, IMP, is an E3 ubiquitin ligase binds and modulates MAP kinase signaling by regulating the scaffolding activity KSR.
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