Targeting RAS signalling pathways in cancer therapy

作者: Julian Downward

DOI: 10.1038/NRC969

关键词: SignallingGeneSignalling pathwaysBiologyNormal cellCancer therapyRas InhibitorCell biologyAnti-apoptotic Ras signalling cascadeMalignant transformation

摘要: … other ways to activate the same pathways. The RAS signalling pathways are now understood in great detail … This work showed great promise for FTIs in the treatment of human cancers. …

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