作者: Julian Downward
DOI: 10.1038/NRC969
关键词: Signalling 、 Gene 、 Signalling pathways 、 Biology 、 Normal cell 、 Cancer therapy 、 Ras Inhibitor 、 Cell biology 、 Anti-apoptotic Ras signalling cascade 、 Malignant transformation
摘要: … other ways to activate the same pathways. The RAS signalling pathways are now understood in great detail … This work showed great promise for FTIs in the treatment of human cancers. …