Scaffolds in vascular regeneration: current status.

摘要: An ideal vascular substitute, especially in <6 mm diameter applications, is a major clinical essentiality blood vessel replacement surgery. Blood vessels are structurally complex and functionally dynamic tissue, with minimal regeneration potential. These have composite extracellular matrix (ECM) arrangement. The interplay between ECM components tissue specific cells gives their specialized functional attributes. core of engineering relies on the challenges creating conduits that match native adequately regenerate vivo. Out numerous concerns, relevance emphasizes much attention toward appropriate choice scaffold material further development strategies. review intended to be focused various approaches materials currently use current state art. Scaffold ranges from natural synthetic, decellularized, even free approach. applicability tubular for vivo under active investigation. A patent conduit an ample endothelial luminal layer can remains unanswered query field small engineering. Besides, scaffolds developed regeneration, should aim at providing substitutes regenerative approach laboratory bench patient bedside.