Laboratory assessment of divaricatic acid against Biomphalaria glabrata and Schistosoma mansoni cercariae
作者： H.A.M.F. Silva , W.N. Siqueira , J.L.F. Sá , L.R.S Silva , M.C.B. Martins
DOI: 10.1016/J.ACTATROPICA.2017.09.019
关键词:
摘要: Abstract In this study, the molluscicidal and antiparasitic activities of divaricatic acid was evaluated, targeting mollusc Biomphalaria glabrata cercariae helminth Schistosoma mansoni. addition, environmental toxicity assessed by bioassay using microcrustacean Artemia salina. Divaricatic showed high against both adult snails (5 μg/mL) embryos (20 μg/mL after 6 h exposure). Similar activity observed in mansoni only a short exposure time (10 μg/mL 30 min The did not show acute test salina at concentrations equal to or below 200 μg/mL. proved be promising substance for elimination snail glabrata, an intermediate host schistosomiasis, as well pathogen, while being non-toxic same concentrations. This is first experimental observation cercaricide acid.
sci-hub.se 参考文章(45)
Isao Yoshimura, Siegfried Huneck, Identification of lichen substances ,(1996)
Heng Luo, Yoshikazu Yamamoto, Jung A Kim, Jae Sung Jung, Young Jin Koh, Jae-Seoun Hur, Lecanoric acid, a secondary lichen substance with antioxidant properties from Umbilicaria antarctica in maritime Antarctica (King George Island) Polar Biology. ,vol. 32, pp. 1033- 1040 ,(2009) , 10.1007/S00300-009-0602-9
Romero M.P.B. Costa, Antônio F.M. Vaz, Haroudo S. Xavier, Maria T.S. Correia, Maria G. Carneiro-da-Cunha, Phytochemical screening of Phthirusa pyrifolia leaf extracts: Free-radical scavenging activities and environmental toxicity South African Journal of Botany. ,vol. 99, pp. 132- 137 ,(2015) , 10.1016/J.SAJB.2015.03.193
Sarah K. Oettl, Jane Hubert, Jean-Marc Nuzillard, Hermann Stuppner, Jean-Hugues Renault, Judith M. Rollinger, Dereplication of depsides from the lichen Pseudevernia furfuracea by centrifugal partition chromatography combined to 13C nuclear magnetic resonance pattern recognition. Analytica Chimica Acta. ,vol. 846, pp. 60- 67 ,(2014) , 10.1016/J.ACA.2014.07.009
Ahmed A. Abdel-Haleem Yousef, Naaema B. EI-Kassas, Ultrastructure and histopathological effects of some plant extracts on digestive gland of Biomphalaria alexandrina and Bulinus truncatus The Journal of Basic & Applied Zoology. ,vol. 66, pp. 27- 33 ,(2013) , 10.1016/J.JOBAZ.2012.12.006
Lenita de Freitas Tallarico, Sueli Ivone Borrely, Natália Hamada, Vanessa Siqueira Grazeffe, Fernanda Pires Ohlweiler, Kayo Okazaki, Amanda Tosatte Granatelli, Ivana Wuo Pereira, Carlos Alberto de Bragança Pereira, Eliana Nakano, None, Developmental toxicity, acute toxicity and mutagenicity testing in freshwater snails Biomphalaria glabrata (Mollusca: Gastropoda) exposed to chromium and water samples Ecotoxicology and Environmental Safety. ,vol. 110, pp. 208- 215 ,(2014) , 10.1016/J.ECOENV.2014.09.005
A. Russo, S. Caggia, M. Piovano, J. Garbarino, V. Cardile, Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: Role of Hsp70 protein Chemico-Biological Interactions. ,vol. 195, pp. 1- 10 ,(2012) , 10.1016/J.CBI.2011.10.005
M Bačkorová, M Bačkor, J Mikeš, R Jendželovský, P Fedoročko, None, Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid. Toxicology in Vitro. ,vol. 25, pp. 37- 44 ,(2011) , 10.1016/J.TIV.2010.09.004
Lidiane Pereira de Albuquerque, Emmanuel Viana Pontual, Giselly Maria de Sá Santana, Luanna Ribeiro Santos Silva, Jaciana dos Santos Aguiar, Luana Cassandra Breitenbach Barroso Coelho, Moacyr Jesus Barreto de Melo Rêgo, Maira Galdino da Rocha Pitta, Teresinha Gonçalves da Silva, Ana Maria Mendonça de Albuquerque Melo, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva, None, Toxic effects of Microgramma vacciniifolia rhizome lectin on Artemia salina, human cells, and the schistosomiasis vector Biomphalaria glabrata. Acta Tropica. ,vol. 138, pp. 23- 27 ,(2014) , 10.1016/J.ACTATROPICA.2014.06.005
Peng-Cheng Lv, Zhu-Ping Xiao, Rui-Qin Fang, Huan-Qiu Li, Hai-Liang Zhu, Chang-Hong Liu, Synthesis, characterization and structure-activity relationship analysis of novel depsides as potential antibacterials. European Journal of Medicinal Chemistry. ,vol. 44, pp. 1779- 1787 ,(2009) , 10.1016/J.EJMECH.2008.04.019