Cartilage repair techniques in the knee: stem cell therapies.

摘要: Among the surgical options for large full-thickness chondral injuries, cell-based therapy has been practiced and its satisfactory outcomes have reported. One area that appears promising is therapies utilizing stem cells. Various tissues within human body contain mesenchymal cells (MSCs) from where these can be harvested. These include bone marrow, adipose, synovium, peripheral blood, umbilical cord. In this article, both preclinical animal studies clinical dealing with use of MSCs cartilage repair knee are reviewed. Majority papers shown results; however, there a limited number high evidence level. Clinical significance cell as compared to other well optimization procedure in terms type delivery method still determined.