The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer : A Report of the Association for Molecular Pathology

摘要: Clinical utility describes the benefits of each laboratory test for that patient. Many stakeholders have adopted narrow definitions clinical molecular testing as applied to targeted pharmacotherapy in oncology, regardless population tested or purpose testing. This definition does not address all important applications diagnostic Definitions consistent with a patient-centered approach emphasize and recognize result's depends on context which it is used are particularly relevant because nature information they provide. Debates surrounding levels types evidence needed properly evaluate value diagnostics increasingly growing body knowledge, stemming from increase genomic medicine, provides many new opportunities improve health care. We challenges defining inherited diseases cancer provide assessment recommendations. Starting modified analytic validity, utility, ethical, legal, social implications model addressing variety purposes, we recommend promotion appropriately valuable contribution patient