Effects of hyaluronan on vascular endothelial growth factor and receptor-2 expression in a rabbit osteoarthritis model
作者： Jian-lin Zhou , Shi-qing Liu , Bo Qiu , Qiong-jie Hu , Jiang-hua Ming
DOI: 10.1007/S00776-009-1329-8
关键词:
摘要: Background Little is known about the expression of vascular endothelial growth factor (VEGF) and its receptor-2 (VEGFR-2) mRNA in cartilage a rabbit osteoarthritis model or influence intraarticular injection hyaluronan (HA) on VEGF VEGFR-2 during process (OA). The therapeutic mechanism HA not completely understood, we hypothesize that through effects VEGFR2. In this study, determined OA assessed against OA.
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HENRY J. MANKIN, HOWARD DORFMAN, LOUIS LIPPIELLO, ANTRA ZARINS, Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. Journal of Bone and Joint Surgery, American Volume. ,vol. 53, pp. 523- 537 ,(1971) , 10.2106/00004623-197153030-00009
M. L. Ho, J. R. Jackson, N. Wei, J. D. Winkler, J. A. L. Minton, Expression of vascular endothelial growth factor in synovial fibroblasts is induced by hypoxia and interleukin 1beta. The Journal of Rheumatology. ,vol. 24, pp. 1253- 1259 ,(1997)
Wan-Uk Kim, Soon Suk Kang, Seung-Ah Yoo, Kyung-Hee Hong, Dong-Goo Bae, Mi-Sook Lee, Seung Woo Hong, Chi-Bom Chae, Chul-Soo Cho, Interaction of Vascular Endothelial Growth Factor 165 with Neuropilin-1 Protects Rheumatoid Synoviocytes from Apoptotic Death by Regulating Bcl-2 Expression and Bax Translocation Journal of Immunology. ,vol. 177, pp. 5727- 5735 ,(2006) , 10.4049/JIMMUNOL.177.8.5727
Hans-Peter Gerber, Thiennu H Vu, Anne M Ryan, Joe Kowalski, Zena Werb, Napoleone Ferrara, None, VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation Nature Medicine. ,vol. 5, pp. 623- 628 ,(1999) , 10.1038/9467
Giuseppe M Campo, Angela Avenoso, Salvatore Campo, Alida M Ferlazzo, Domenica Altavilla, Alberto Calatroni, Efficacy of treatment with glycosaminoglycans on experimental collagen-induced arthritis in rats Arthritis Research & Therapy. ,vol. 5, pp. 1- 10 ,(2003) , 10.1186/AR748
Thomas Pufe, Viola Harde, Wolf Petersen, Mary B Goldring, Bernhard Tillmann, Rolf Mentlein, Vascular endothelial growth factor (VEGF) induces matrix metalloproteinase expression in immortalized chondrocytes. The Journal of Pathology. ,vol. 202, pp. 367- 374 ,(2004) , 10.1002/PATH.1527
M. Murata, K. Yudoh, K. Masuko, The potential role of vascular endothelial growth factor (VEGF) in cartilage: How the angiogenic factor could be involved in the pathogenesis of osteoarthritis? Osteoarthritis and Cartilage. ,vol. 16, pp. 279- 286 ,(2008) , 10.1016/J.JOCA.2007.09.003
Thomas Pufe, Wolf Petersen, Bernhard Tillmann, Rolf Mentlein, The splice variants VEGF121 and VEGF189 of the angiogenic peptide vascular endothelial growth factor are expressed in osteoarthritic cartilage. Arthritis & Rheumatism. ,vol. 44, pp. 1082- 1088 ,(2001) , 10.1002/1529-0131(200105)44:5<1082::AID-ANR188>3.0.CO;2-X
Mehmet Halici, Sinan Karaoglu, Ozlem Canoz, Sevki Kabak, Ali Baktir, Sodium hyaluronate regulating angiogenesis during Achilles tendon healing Knee Surgery, Sports Traumatology, Arthroscopy. ,vol. 12, pp. 562- 567 ,(2004) , 10.1007/S00167-004-0536-2
Kenji Inoue, Kayo Masuko-Hongo, Masahiro Okamoto, Kusuki Nishioka, Induction of vascular endothelial growth factor and matrix metalloproteinase-3 (stromelysin) by interleukin-1 in human articular chondrocytes and synoviocytes. Rheumatology International. ,vol. 26, pp. 93- 98 ,(2005) , 10.1007/S00296-004-0513-6