Increasing Volume and Changing Characteristics of Invasive Pulmonary Aspergillosis on Sequential Thoracic Computed Tomography Scans in Patients With Neutropenia
作者： Denis Caillot , Jean-Francois Couaillier , Alain Bernard , Olivier Casasnovas , David W. Denning
DOI: 10.1200/JCO.2001.19.1.253
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摘要: PURPOSE: In patients with neutropenia, thoracic computed tomography (CT) halo and air-crescent signs are recognized as major indicators of invasive pulmonary aspergillosis (IPA). Nevertheless, the exact timing CT images is not well known. PATIENTS AND METHODS: Seventy-one scans were analyzed in 25 neutropenia surgically proven IPA. RESULTS: On first day IPA diagnosis early scan (d0), a typical sign was observed 24 patients. At that time, median number lesions two (range, one to six), involvement bilateral 12 cases. The present 68%, 22%, 19% cases on d3, d7, d14, respectively. Similarly, seen 8%, 28%, 63% same days. Otherwise, nonspecific air-space consolidation aspect 31%, 50%, 18% analysis calculated aspergillary volumes showed that, despite antifungal treatment, the...
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