Cherubism. Histo-enzymological and ultrastructural study
作者： G. Chomette , M. Auriol , F. Guilbert , J.M. Vaillant
DOI: 10.1016/S0901-5027(88)80043-2
关键词:
摘要: The 3 cases of cherubism reported affected the mandible. They were all studied by means histo-enzymological and ultrastructural methods. This study demonstrated stages in morphological evolution disease, corroborated clinical data. 1st stage was characterized an osteolytic granuloma with round, fusiform giant-cells a high level activity acid phosphatase. 2nd showed repair proliferation highly active fibroblasts (increase leucine aminopeptidase). 3rd exhibited osteogenesis alkaline phosphatase ATPase. pathogenesis this rare osteodysplasia is discussed.
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