Biological evaluation of synthetic chalcone and flavone derivatives as anti-inflammatory agents

作者: Nelly Mateeva , Madhavi Gangapuram , Elizabeth Mazzio , Suresh Eyunni , Karam F. A. Soliman

DOI: 10.1007/S00044-014-1214-7

关键词:

摘要: Flavonoids and chalcones are natural plant derived compounds with inherent therapeutic value for a range of human pathologies. In this study, a series of 24 substituted chalcones and …

参考文章(45)
Alessandra Choqueta Toledo, Camila Pivari Pedroso Sakoda, Adenir Perini, Nathalia Montouro Pinheiro, Renato Moschella Magalhaes, S Grecco, Iolanda de Fátima Lopes Calvo Tiberio, NO Câmara, Milton de Arruda Martins, Joao Henrique Ghilardi Lago, Carla Máximo Prado, None, Flavonone treatment reverses airway inflammation and remodelling in an asthma murine model. British Journal of Pharmacology. ,vol. 168, pp. 1736- 1749 ,(2013) , 10.1111/BPH.12062
Laddawan Senggunprai, Veerapol Kukongviriyapan, Auemduan Prawan, Upa Kukongviriyapan, Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway Phytotherapy Research. ,vol. 28, pp. 841- 848 ,(2014) , 10.1002/PTR.5061
Youngpyo Nam, Mijung Choi, Heehong Hwang, Maan-Gee Lee, Byoung-Mog Kwon, Won-Ha Lee, Kyoungho Suk, Natural flavone jaceosidin is a neuroinflammation inhibitor. Phytotherapy Research. ,vol. 27, pp. 404- 411 ,(2013) , 10.1002/PTR.4737
Gajanan G. Mandawad, Bhaskar S. Dawane, Supriya D. Beedkar, Chandrahas N. Khobragade, Omprakash S. Yemul, Trisubstituted thiophene analogues of 1-thiazolyl-2-pyrazoline, super oxidase inhibitors and free radical scavengers. Bioorganic & Medicinal Chemistry. ,vol. 21, pp. 365- 372 ,(2013) , 10.1016/J.BMC.2012.09.060
Jeremy P.E. Spencer, Katerina Vafeiadou, Robert J. Williams, David Vauzour, Neuroinflammation: Modulation by Flavonoids and Mechanisms of Action Molecular Aspects of Medicine. ,vol. 33, pp. 83- 97 ,(2012) , 10.1016/J.MAM.2011.10.016
Mastura Monif, Geoffrey Burnstock, David A. Williams, Microglia: proliferation and activation driven by the P2X7 receptor. The International Journal of Biochemistry & Cell Biology. ,vol. 42, pp. 1753- 1756 ,(2010) , 10.1016/J.BIOCEL.2010.06.021
Shizuka Hirai, Young-II Kim, Tsuyoshi Goto, Min-Sook Kang, Mineka Yoshimura, Akio Obata, Rina Yu, Teruo Kawada, Inhibitory effect of naringenin chalcone on inflammatory changes in the interaction between adipocytes and macrophages. Life Sciences. ,vol. 81, pp. 1272- 1279 ,(2007) , 10.1016/J.LFS.2007.09.001
K. Shrivastava, G. Llovera, M. Recasens, M. Chertoff, L. Giménez-Llort, B. Gonzalez, L. Acarin, Temporal expression of cytokines and signal transducer and activator of transcription factor 3 activation after neonatal hypoxia/ischemia in mice. Developmental Neuroscience. ,vol. 35, pp. 212- 225 ,(2013) , 10.1159/000348432
Chi-Chen Lin, Ching-Liang Chu, Chin-Sheng Ng, Ching-Yen Lin, Der-Yuan Chen, I.-Hong Pan, Kao-Jean Huang, Immunomodulation of phloretin by impairing dendritic cell activation and function. Food & Function. ,vol. 5, pp. 997- 1006 ,(2014) , 10.1039/C3FO60548E
Min Li, Fu-rong Dai, Xiao-ping Du, Qi-dong Yang, Yuxiang Chen, Neuroprotection by Silencing iNOS Expression in a 6-OHDA Model of Parkinson’s Disease Journal of Molecular Neuroscience. ,vol. 48, pp. 225- 233 ,(2012) , 10.1007/S12031-012-9814-5