Diagnostic value of soluble mesothelin-related peptides for malignant mesothelioma: A meta-analysis
作者： Ling Luo , Huan-Zhong Shi , Qiu-Li Liang , Jing Jiang , Shou-Ming Qin
DOI: 10.1016/J.RMED.2009.05.017
关键词:
摘要: Summary Background Serum concentrations of soluble mesothelin-related peptides (SMRP) have been reported to be higher in patients with malignant mesothelioma than healthy subjects and non-malignant diseases. The aim the present meta-analysis was establish overall diagnostic accuracy measurement SMRPs for diagnosing mesothelioma. Methods After a systematic review English language studies, sensitivity, specificity, other measures serum diagnosis were pooled using random-effects models. receiver operating characteristic curves used summarize test performance. Results Eleven publications from 12 studies met our inclusion criteria. summary estimates included sensitivity 0.64 (95% confidence interval 0.61–0.68), specificity 0.89 (0.88–0.90), positive likelihood ratio 7.10 (4.44–11.35), negative 0.39 (0.31–0.48), odds 19.35 (10.95–34.17). Conclusions SMRP determination plays role results assays should interpreted parallel clinical findings conventional tests.
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sci-hub.se 参考文章(40)
Vamvakas Ec, Meta-analyses of studies of the diagnostic accuracy of laboratory tests : A review of the concepts and methods Archives of Pathology & Laboratory Medicine. ,vol. 122, pp. 675- 686 ,(1998)
Systematic Reviews in Health Care BMJ Publishing Group. ,(2001) , 10.1002/9780470693926
Gordon H. Guyatt, Drummond Rennie, Deborah J. Cook, Maureen O. Meade, Users' guides to the medical literature : a manual for evidence-based clinical practice McGraw Hill Medical/JAMA & Archives Journals. ,(2002)
Masanori Onda, Satoshi Nagata, Mitchell Ho, Tapan K. Bera, Raffit Hassan, Richard H. Alexander, Ira Pastan, Megakaryocyte Potentiation Factor Cleaved from Mesothelin Precursor Is a Useful Tumor Marker in the Serum of Patients with Mesothelioma Clinical Cancer Research. ,vol. 12, pp. 4225- 4231 ,(2006) , 10.1158/1078-0432.CCR-06-0472
Q-L Liang, H-Z Shi, X-J Qin, X-D Liang, J Jiang, H-B Yang, Diagnostic accuracy of tumour markers for malignant pleural effusion: a meta-analysis. Thorax. ,vol. 63, pp. 35- 41 ,(2008) , 10.1136/THX.2007.077958
K. Chang, I. Pastan, Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 93, pp. 136- 140 ,(1996) , 10.1073/PNAS.93.1.136
Michel M. van den Heuvel, Catharina M. Korse, Johannes M.G. Bonfrer, Paul Baas, Non-invasive diagnosis of pleural malignancies: the role of tumour markers. Lung Cancer. ,vol. 59, pp. 350- 354 ,(2008) , 10.1016/J.LUNGCAN.2007.08.030
Bogdan-Dragos Grigoriu, Arnaud Scherpereel, Patrick Devos, Bachar Chahine, Marc Letourneux, Pierre Lebailly, Marc Grégoire, Henri Porte, Marie-Christine Copin, Philippe Lassalle, Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment. Clinical Cancer Research. ,vol. 13, pp. 2928- 2935 ,(2007) , 10.1158/1078-0432.CCR-06-2144
Bruce W.S. Robinson, Jenette Creaney, Richard Lake, Anna Nowak, Arthur William Musk, Nicholas de Klerk, Pernilla Winzell, Karl Erik Hellstrom, Ingegerd Hellstrom, Soluble mesothelin-related protein—A blood test for mesothelioma Lung Cancer. ,vol. 49, ,(2005) , 10.1016/J.LUNGCAN.2005.03.020
Kota Iwahori, Tadashi Osaki, Satoshi Serada, Minoru Fujimoto, Hidekazu Suzuki, Yoshiro Kishi, Akihito Yokoyama, Hironobu Hamada, Yoshihiro Fujii, Kentaro Yamaguchi, Tomonori Hirashima, Kaoru Matsui, Isao Tachibana, Yusuke Nakamura, Ichiro Kawase, Tetsuji Naka, Megakaryocyte potentiating factor as a tumor marker of malignant pleural mesothelioma: Evaluation in comparison with mesothelin Lung Cancer. ,vol. 62, pp. 45- 54 ,(2008) , 10.1016/J.LUNGCAN.2008.02.012