An expedient approach to highly enantioenriched cyclic nitrones mediated by robust and recoverable C3-symmetric cinchonine-squaramide catalysts
作者： Xin Han , Xiangfei Wu , Chang Min , Hai-Bing Zhou , Chune Dong
DOI: 10.1039/C2RA21162A
关键词:
摘要: The C3-symmetric cinchonine-squaramide catalyzed asymmetric Michael addition of β-ketosulfones to nitroalkenes is presented. Subsequent transformation leads chiral cyclic nitrones with excellent results (up 85% yield and >99% ee). catalyst can be recovered reused for six cycles without losing activity selectivity.
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sci-hub.se 参考文章(52)
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