The effects of pulmonary diseases on histologic types of lung cancer in both sexes: a population-based study in Taiwan.

摘要: The associations between pulmonary diseases (asthma, chronic obstructive disease [COPD], and tuberculosis [TB]) subsequent lung cancer risk have been reported, but few studies investigated the association with different histologic types of cancer. Patients newly diagnosed from 2004 to 2008 were identified National Health Insurance Research Database in Taiwan. Histologic further confirmed using Taiwan Cancer Registry Database. Cox proportional hazards regression was used calculate hazard ratio (HR) asthma, COPD, TB estimate specific During study period, 32,759 cases 15,219,024 insurants aged 20 years older. In men women, adjusted HR estimates squamous cell carcinoma respectively 1.37 (95 % confidence interval [CI], 1.21–1.54) 2.10 CI, 1.36–3.23) for TB, 1.52 1.42–1.64) 1.50 1.21–1.85) 1.66 1.56–1.76) 1.44 1.19–1.74) COPD. Similarly, adenocarcinoma 1.33 1.19–1.50) 1.86 1.57–2.19) 1.13 1.05–1.21) 1.18 1.09–1.28) 1.42–1.59) 1.25–1.42) HRs small 1.24 1.01–1.52) 2.23 1.17–4.25) 1.51 1.35–1.69) 1.63 1.16–2.27) 1.39 1.26–1.53) 1.78 1.33–2.39) Asthma, associated an increased all major subtypes highest among women TB.